Sloppy Joe Biscuit Casserole

This Sloppy Joe Biscuit Casserole turns a classic messy sandwich into an easy, oven-baked dish that the whole family loves. It combines savory ground beef with tangy sauce and fluffy biscuits for a warm, comforting meal that’s perfect for busy weeknights or casual gatherings.

I first tried this casserole on a hectic weeknight and was amazed how everyone, including my picky eaters, dug in without complaint. Now it’s a go-to for easy, crowd-pleasing dinners.

Ingredients

• Ground beef: the base for rich, savory flavor choose 80/20 for juiciness
• Ketchup: adds sweetness and tang quality brands give best taste
• Brown sugar: balances acidity with caramel notes
• Worcestershire sauce: deepens umami adds complexity to the sauce
• Mustard: brings a mild tang that cuts through richness
• Garlic powder and onion powder: essential for layering flavor without fresh ingredients
• Salt: enhances all the other flavors
• Biscuits cut into quarters: provide a tender, fluffy texture that soaks up the sauce store-bought refrigerated dough works well for convenience
• Cheddar cheese shredded: melts on top to add gooey, savory richness sharp cheddar gives extra punch

Step-by-Step Instructions

Preheat the Oven and Prep the Pan:

Set your oven to 350 degrees Fahrenheit and lightly coat a 9 x 13 baking pan with cooking spray to prevent sticking and help with easy cleanup.

Cook the Ground Beef:

In a cast iron skillet over medium heat, cook the ground beef until it is no longer pink. Once cooked, drain off the excess fat to keep the dish from getting greasy.

Create the Sloppy Joe Sauce:

Add ketchup, water, brown sugar, Worcestershire sauce, mustard, garlic powder, onion powder, and salt to the beef. Stir to combine fully and let it simmer gently for about five minutes to meld the flavors.

Combine with Biscuits:

Remove the skillet from heat and transfer the meat mixture to a medium-sized bowl. Add the quartered biscuits and toss everything together so the biscuits are evenly coated with the sauce.

Assemble and Bake:

Pour the biscuit and meat mixture into your prepared baking dish. Sprinkle the shredded cheddar cheese on top evenly across the surface. Place the pan in the oven and bake for 28 to 30 minutes until the biscuits are golden brown and cooked through.

Serve Warm:

Carefully remove the casserole from the oven and serve immediately for a cozy and satisfying meal.

Save

Cheddar cheese is my favorite part of this dish because it creates a deliciously gooey top layer that pulls apart with every serving. I remember making this for my kids after school, and their eyes lit up the moment the cheese started bubbling.

Storage Tips

Store leftovers in an airtight container in the refrigerator for up to three days. To reheat, cover loosely with foil and warm in the oven at 350 degrees until heated through to keep the biscuits soft and cheese melty.

Ingredient Substitutions

Ground turkey or plant-based crumbles can replace ground beef for a lighter or vegetarian option. Feel free to swap cheddar for mozzarella or pepper jack for a different cheese profile. Biscuits can be homemade or from refrigerated dough depending on your preference.

Serving Suggestions

Serve this casserole with a side of fresh green salad or steamed veggies to balance the richness. It also pairs well with classic coleslaw or a simple fruit salad for a complete family meal.

Cultural Context

Sloppy joes are a nostalgic American comfort food often served as sandwiches, but this casserole version originated as a creative take on bubble-up biscuits, combining convenience and flavor. It’s great for family meals or potlucks where ease and taste are equally important.

Recipe FAQs

→ What type of ground meat works best?

Ground beef is traditional, but ground turkey can be used for a leaner option without sacrificing flavor.

→ Can I prepare this dish in advance?

Yes, you can assemble it ahead of time and refrigerate before baking. Just add extra baking time if baking from cold.

→ What kind of biscuits should I use?

Flaky refrigerated biscuits work well, as they soak up the savory sauce and bake into tender pockets.

→ How can I add more spice to this dish?

Incorporate a pinch of cayenne pepper or a dash of hot sauce into the meat mixture for a gentle kick.

→ Is there a recommended cheese type?

Sharp cheddar cheese provides great melt and flavor, but feel free to use a blend of cheeses if preferred.