Baked Italian Sub Sandwiches

Highlight: Satisfying Main Dishes for Every Occasion

This dish showcases baked Italian subs bursting with layers of salami, ham, pepperoni, and provolone cheese, complemented by shredded lettuce, sliced tomatoes, and black olives. The toppings are enhanced with Italian dressing and oregano, then wrapped and baked until the cheese melts and bread crisps perfectly. Quick to prepare and easy to customize with extra spices or cheeses, these subs make a satisfying meal for gatherings or casual lunches.

A woman in a blue apron holding a plate of food.
Crafted By Sophie
Updated on Wed, 07 Jan 2026 19:44:03 GMT
A large sub sandwich with meat, cheese, and onions. Save
A large sub sandwich with meat, cheese, and onions. | myhomemademeal.com

These baked Italian sub sandwiches bring together savory layers of meat, cheese, and crisp fresh vegetables all toasted to perfection. They make a fantastic choice for family dinners or any casual get-together where everyone delights in big, bold flavors and comforting warmth.

I remember making this during a weekend game day and how everyone reached for seconds without hesitation. It quickly became a favorite for any gathering in our home.

Ingredients

  • Italian bread: the sturdy base that crisps up wonderfully in the oven, choose a fresh loaf with a crisp crust and soft center
  • Sliced salami: adds rich, slightly spicy flavor, look for good quality cured meats for best taste
  • Sliced ham: provides a mild, sweet balance
  • Sliced pepperoni: brings a peppery kick and additional depth
  • Provolone cheese: melts beautifully with a mild, slightly smoky flavor
  • Shredded lettuce: adds a fresh, crunchy contrast
  • Tomato, sliced: juicy and bright, ripe tomatoes work best
  • Sliced black olives: contribute a salty, briny element
  • Italian dressing: ties all the flavors together with herbs and tang, opt for your favorite bottled variety or homemade
  • Oregano: sprinkled on top for an aromatic herbaceous finish

Step-by-Step Instructions

Slicing and Preheating:
Preheat your oven to 350 degrees Fahrenheit. Carefully slice the Italian bread in half lengthwise to create the sandwich base and top.
Layer the Meats and Cheese:
On the bottom half of the bread, layer the sliced salami, ham, pepperoni, and provolone cheese evenly. This creates the rich foundation and ensures every bite has a good balance of flavors.
Add the Fresh Vegetables:
Top the cheese with shredded lettuce, followed by tomato slices and black olives. These fresh ingredients add crispness and brightness to the sandwich.
Dress and Season:
Drizzle the Italian dressing evenly over the vegetables to keep the sandwich moist and flavorful. Sprinkle oregano over the top to enhance the Italian herbs and spice notes.
Wrap and Bake:
Place the top half of the bread back on the sandwich and wrap the entire sub tightly in aluminum foil. Bake it in the preheated oven for 15 to 20 minutes, until the cheese has melted and the bread is toasted and golden.
Serve:
Remove the sandwich from the oven, unwrap it carefully, slice into servings, and serve warm for the best melting taste experience.
A baked Italian sub sandwich with meat, cheese, tomatoes, onions, and peppers. Save
A baked Italian sub sandwich with meat, cheese, tomatoes, onions, and peppers. | myhomemademeal.com

Provolone is my favorite ingredient here because its mild gooey texture perfectly complements the stronger flavors of salami and pepperoni. I always think back to the first time we served this at a family picnic where everyone raved about the melty cheese and crispy bread combo.

Storage Tips

Keep any leftovers wrapped tightly in foil or plastic wrap and stored in the refrigerator for up to two days. Reheat wrapped in the oven to restore the crisp bread and melted cheese rather than microwaving which can make the bread soggy.

Ingredient Substitutions

Try swapping provolone for mozzarella or Swiss cheese for a different melt and flavor. Use turkey or roast beef instead of ham or salami for a leaner version. For dressings, a vinaigrette or even a spicy mayo adds a yummy twist.

Serving Suggestions

Pair these subs with a simple side like potato chips, a crisp green salad, or a handful of pickles to complement the rich sandwich flavors. A cold soda or sparkling water makes a refreshing drink choice.

Cultural Context

Italian subs or hoagies are classic American sandwiches inspired by Italian American communities. They showcase layers of cured meats, cheeses, and fresh vegetables reflecting traditional antipasto platters but turned into a handheld meal perfect for picnics and casual dining.

Recipe FAQs

→ What type of bread works best?

A sturdy Italian loaf is ideal as it holds the fillings well and crisps nicely when baked.

→ Can I substitute meats in this sandwich?

Yes, you can switch salami, ham, and pepperoni for other cured meats or even roasted vegetables for a vegetarian twist.

→ How long should I bake the sandwich?

Bake for 15-20 minutes at 350°F (175°C) until the cheese melts and the bread is toasted to your preference.

→ What are good additional toppings?

Sliced jalapeños add a spicy kick, while extra herbs like basil or parsley can enhance the flavor profile.

→ Can the sandwiches be prepared ahead of time?

Yes, assemble and wrap the sandwiches in foil, then bake just before serving for freshness and convenience.

Baked Italian Sub Sandwiches

Savory baked Italian subs with layered meats, provolone, fresh vegetables, and herbs, great for sharing or a hearty meal.

Prep Time
15 minutes
Cooking Duration
20 minutes
Overall Time
35 minutes
Crafted By: Sophie

Recipe Type: Main Dishes

Preparation Complexity: Beginner-Friendly

Regional Cuisine: Italian

Servings Output: 4 Serving Size (4 sandwiches)

Dietary Choices: Suitable for Vegetarians

Everything You’ll Need

→ Bread

01 1 loaf Italian bread

→ Meats

02 8 oz sliced salami
03 8 oz sliced ham
04 8 oz sliced pepperoni

→ Cheese

05 8 oz provolone cheese, sliced

→ Vegetables

06 1 cup shredded lettuce
07 1 tomato, sliced
08 1/4 cup sliced black olives

→ Condiments & Spices

09 1/4 cup Italian dressing
10 1 tbsp dried oregano

Steps to Cook

Step 01

Set the oven to 350°F and allow it to fully preheat.

Step 02

Slice Italian bread lengthwise into two halves.

Step 03

Arrange salami, ham, pepperoni, and provolone cheese evenly on the bottom half of the bread.

Step 04

Top the cheese layer with shredded lettuce, tomato slices, and black olives.

Step 05

Drizzle Italian dressing over the vegetable layer, then sprinkle dried oregano evenly on top.

Step 06

Place the top half of the bread over the fillings and wrap the entire sandwich tightly in aluminum foil.

Step 07

Bake wrapped sandwich in the preheated oven for 15 to 20 minutes until cheese melts and bread crisps.

Step 08

Remove sandwich from oven, unwrap, slice into portions, and serve immediately.

Extra Suggestions

  1. Customize with preferred meats and cheeses. For added heat, include sliced jalapeños. Prepare ahead and bake before serving.

Must-Have Equipment

  • Oven
  • Aluminum foil
  • Sharp knife

Allergy Information

Always check ingredient details for potential allergens. Consult an expert if you're uncertain.
  • Contains dairy and gluten
  • May contain pork

Nutritional Highlights (per portion)

Nutritional information is shared for guidance and isn't meant to replace expert medical advice.
  • Caloric Content: 450
  • Fat Breakdown: 25 grams
  • Carbohydrate Breakdown: 40 grams
  • Protein Count: 20 grams